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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRC1
All Species:
21.82
Human Site:
S169
Identified Species:
48
UniProt:
O43663
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43663
NP_003972.1
620
71607
S169
T
L
R
E
T
K
A
S
R
R
E
E
F
V
S
Chimpanzee
Pan troglodytes
XP_510600
770
87232
S333
T
L
R
D
T
K
A
S
R
R
E
E
F
V
S
Rhesus Macaque
Macaca mulatta
XP_001098763
640
74381
S169
T
L
R
E
T
K
A
S
R
R
E
E
F
V
S
Dog
Lupus familis
XP_849989
620
71878
S169
T
L
R
E
T
K
A
S
R
R
E
E
F
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q99K43
603
70244
S169
T
L
R
E
T
K
E
S
R
R
E
E
F
V
N
Rat
Rattus norvegicus
NP_001100999
606
70580
S169
T
L
R
E
T
K
E
S
R
H
E
Q
F
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073221
262
30135
Frog
Xenopus laevis
NP_001080868
609
71186
R168
G
L
S
A
E
K
E
R
R
E
A
E
F
K
S
Zebra Danio
Brachydanio rerio
NP_956528
605
70353
R169
C
L
T
A
E
K
E
R
R
H
K
E
F
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572659
607
71048
Q169
Q
L
R
D
Q
R
V
Q
R
L
R
D
M
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785901
748
86941
Q171
T
L
T
A
E
K
D
Q
R
H
K
T
F
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.3
89.8
93
N.A.
81.2
81.2
N.A.
N.A.
28.5
61.9
59
N.A.
22.2
N.A.
N.A.
31.2
Protein Similarity:
100
78.4
92.5
95.8
N.A.
88.3
88.8
N.A.
N.A.
35.6
76.2
73.3
N.A.
43.5
N.A.
N.A.
48.1
P-Site Identity:
100
93.3
100
93.3
N.A.
86.6
73.3
N.A.
N.A.
0
40
40
N.A.
20
N.A.
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
N.A.
0
40
53.3
N.A.
40
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
28
0
0
37
0
0
0
10
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
10
0
0
0
0
10
0
10
0
% D
% Glu:
0
0
0
46
28
0
37
0
0
10
55
64
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
82
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
28
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
82
0
0
0
0
19
0
0
10
0
% K
% Leu:
0
91
0
0
0
0
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
28
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
10
0
0
19
0
0
0
10
0
0
0
% Q
% Arg:
0
0
64
0
0
10
0
19
91
46
10
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
55
0
0
0
0
0
0
46
% S
% Thr:
64
0
19
0
55
0
0
0
0
0
0
10
0
10
10
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
64
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _